[CHEM 360] Next-Generation Antimicrobials
This course explores the chemistry of antibiotics, including their chemical structures, mechanisms of antibiotic action, mechanisms of bacterial resistance, methods of drug discovery, and stewardship and policy. Students engage in critical reading and discussion of scientific literature. During the laboratory component of the course, students discover and characterize antibiotic-producing bacteria from soil. Techniques include aseptic microbiological work, PCR and introductory bioinformatics (BLAST, and antiSMASH), chemical extraction, and biochemical assays. Students engage in experimental design during a semester-long research project and communicate their findings by preparing and presenting a poster about their research project.