Beloit Summer Biomedical Research Scholars Program
The Beloit College Biomedical Research Scholars Program is an 8-week program of mentored laboratory research for current Beloit College students. Biomed Scholars will receive a stipend, must enroll in one unit of Biology 392: Independent Research in Biology, and pay summer tuition for this course. Scholars may contract with the college for room and board. The stipend has been calculated to cover these costs. The program will run during June and July.
To apply, students should
- submit an application form.
- request two reference reports from faculty members or work supervisors; at least one report must be from a Beloit College faculty member. Potential mentors are eligible to submit recommendations.
- email an unofficial transcript from the Portal to Yaffa Grossman, firstname.lastname@example.org
Application materials are due on March 20, 2014, for full consideration.
Physiological stress response, Professor Katie Johnson
Humans and animals react to physiological and psychological stress through complex mechanisms involving the nervous and endocrine systems. Student research projects will focus on the activation of the endocrine system, measured by changes in circulating hormones levels, in humans and animals in response to physical stressors, such as exercise. Changes in hormone levels will be assessed through the collection of saliva, which will then be analyzed for cortisol and possibly other stress hormones.
Oxygen binding to hemoglobin, Professor Ted Gries
Using a tonometer, the biomedical scholar will test the hypothesis from the Monod-Wyman-Changeux (MWC) model for oxygen binding to hemoglobin that protein conformational changes are isolated to a single equilibrium constant and do not contribute to the individual oxygen site binding constants. While widely accepted, this component of the MWC model has not been experimentally verified.
Molecular and bioinformatic investigations of plant disease resistance mechanisms, Professor Amy Briggs
Previous studies have shown the importance of folypolyglutamate synthetase (FPGS) enzymes in early plant developmental pathways, and preliminary bioinformatic studies indicate that this enzyme may also be essential for proper immune response activation. The Arabidopsis thaliana genome encodes multiple FPGS proteins, and so the project for this summer will involve genetic screening for double and triple knockouts of FPGS genes and the testing these of knockouts for dysfunctions in various plant immune responses (such as cell wall reinforcement and bacterial pathogen growth). This project will also include the bioinformatic analysis of global gene expression changes in plants undergoing a variety of immune stressors, in an attempt to identify novel mechanisms of transcriptional activation during plant defense responses.
The Evolution of Host Reproductive Traits Under Selection by Pathogens, Professor Deanna Soper
Host-pathogen coevolution is predicted to influence the evolution of mating behaviors, gametic morphology, and gametic function. Currently, I use the C. elegans and Serratia marcescens system to test the hypothesis that host-pathogen coevolution selects for reproductive traits that increase the genetic diversity of host populations. Student projects may range from experimental evolution studies to behavioral and cellular assays to investigate the reproductive biology of C. elegans.
Research opportunities in university labs may be possible
Placement of students in a research university lab may be possible depending upon applicant interests and availability of openings. If you are interested in a university placement, contact Professor Yaffa Grossman at email@example.com and describe your interests in your application.