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DNA Topology:
Somewehere Between Biology, Art and Mathematics
Electron Micrographs from Knot Exhibit at University of Wales at Bangor
Knot Images Plotted by KnotPlot
Several fascinating aspects of DNA structure, both on topological and on geometrical levels, aid us in understanding DNA function. Alpha-helical coiling of DNA strands is only the starting structural element, which we usually associate with DNA structure. Supercoiling, knotting and linking are further structural elements of DNA. Because supercoiling, knotting and linking are important in cellular processes, we should understand their geometry and topology.
The basic concepts of knotting, linking and supercoiling can be made simple
enough to be understood by biology undergraduates. However, the level at
which these concepts are presented is often too professional and specialized.
As a part of my special
project in Mathematical Biology, I will attempt to present a few ideas
of DNA topology and geometry, whose scientific, mathematical and aesthetic
aspects will hopefully motivate further interest in this new and exciting
field.
This site is designed and maintained by Srebrenka Robic.
Email comments to robics@stu.beloit.edu